meds that trigger psoriasis……..
Question:
It is true that some people may flare in their psoriasis of the skin from some NSAIDs, and naprosyn (generic name naproxen) is an NSAID. However, this is not an automatic thing. Not everybody will flare from every NSAID. Some people may not flare from NSAIDs at all. I am one of these. For me, strange though it may sound, I actually get a huge amount of improvement in my skin from NSAIDs. When my PA (psoriatic arthritis) first flared up big time, my only treatment was NSAID treatment, and that alone brought my decades long 60 – 70% coverage of psoriasis down to about 10%. I know that doesn’t make sense, but it is how it worked for me. Of course NSAIDs do have lots of other serious potential side effects, so do watch that you do not mix NSAIDs, that you take only with a full meal, and that you watch for signs of bleeding or pain in the stomach or intestinal tract. As to the safety of tylenol or other drugs containing acetaminophen, this is a real drug and should NEVER be taken without care as to the total daily dose you are getting. The difference between the therapeutic dose and the dose that can cause severe liver damage is very small, so keep track of how much you take in a day and NEVER exceed the recommended daily dose. If you drink alcohol regularly CUT THE DAILY MAXIMUM DOSE YOU MAY TAKE IN HALF. The most common cause of liver damage resulting in needing a liver transplant is taking an overdose of acetaminophen (tylenol or combinations of other drugs with acetaminophen). Don’t forget to add into the daily dose you are taking any OTHER drugs you may be taking that also contain acetaminophen. Ex: vicodin, percocet, darvocet, ultracet, etc, as well as many over-the-counter drugs like cough med’s, headache preparations, etc. As to other drugs that may exacerbate psoriasis, I have saved the following information from Dr. Susan Hoch, a practicing rheumatologist and professor of rheumatology in Philadelphia: You bring up a good point of what drugs may exacerbate psoriasis. The Plaquenil(hydroxychloroquine) exacerbation of psoriasis is well known to rheumatologists. The exacerbation of psoriasis by beta blockers is less well known as it is hidden in the dermatology literature and I doubt that your GP has the time to read such specialty journals. So to help him or her out, here are some references. You may wish to go to PubMed, which is at the Web Site of the National Library of Medicine to print out the abstracts yourself. That URL is ncbi.nlm.nih.gov. 1. Wolf R et al. Inducition of psoriasiform changes in guinea pig skin by propranolol. International Journal of Dermatology 33:811-814, Nov 1994 Beta blockers given orally to guinea pigs alone do not cause these changes. However, when the oral propranolol is combined with a weekly injection of Freund’s adjuvant, the guinea pigs get psoriasiform lesions. 2. Halevy, S and Livni E. Psoriasis and psoriasiform eruptions associated with propranolol-the role of an immunologic mechanism. Archives of Dermatological Research 283:472-473, 1991 3. Heng MV, Heng MK. Beta-adrenergic an tagonist-induced psoriasiform eruption. Clinical and Pathogenetic aspects. Internation Journal of Dermatology. 27:619-627, Nov 1988 And the best of all a general review article on this whole subject. Abel EA et al. Drugs in the Exacerbation of Psoriasis Journal of the American Academy of Dermatology 15(5 Pt 1):1007-1022, 1986 This is a review with 129 references. Hope this is helpful. DrSusan – Hide quoted text — Show quoted text ->Be Aware of Medications >That May Cause Psoriasis to Flare >There are a few medicines prescribed for other health problems that can >worsen psoriasis for some people. They are listed below. If your >psoriasis is flaring, review the medications you are using for >arthritis, blood pressure, migraine or other pain, tremors, malaria, or >liver or intestinal infections caused by microscopic protozoa. (Giardia >is one example of a protozoal infection. Malaria is another.) >The following medicines may cause psoriasis to flare: >Antimalarials – A medical report has shown that 31 percent of those >with psoriasis who used antimalarials such as quinacrine, chloroquine >and hydroxychloroquine experienced an "acute generalized eruption" of >psoriasis. It usually develops two to three weeks after the drug is >taken. Although all three types have been implicated in causing adverse >incidents, hydroxychloroquine has a lower incidence, 19 percent. >Doxycycline may be an alternative. >Lithium – Lithium, a drug used to treat manic depression and other >psychiatric disorders, aggravates psoriasis in about 50 percent of >those who take it. It is difficult to completely clear a person taking >lithium. Sometimes reducing the dose of lithium may help to improve >psoriasis. Several alternatives to lithium exist. Consult your >physician. >Inderal and other beta blocker medications – Researchers have reported >that Inderal aggravates psoriasis in approximately 25 to 30 percent of >patients. It is not known if all beta blocker high blood pressure >medications worsen psoriasis, but they may have that potential. >Sometimes other medications can be substituted; however, it is possible >to clear psoriasis even if you must stay on the beta blocker.
Best regards,
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I strongly suspected that my initial onset of Diabetes (Adult onset Type II) triggered some of my psoriasis on my fingers and some on my face. It was too coincidental to me that soon after my diabetes diagnosis that the P started appearing, and in the case of my bleeding finger tips and splitting finger nails, it was quite painful. One diabetes doctor told me that one possible reason for this, in my case anyway, that my onset of diabetes caused my blood-sugar levels to rise to very high levels and the body’s natural defense mechanism for this is trying to pass the excess sugar in the blood by urinating it out. The body attemps to find any and all water content it can find to help send to the bladder to "flush out" the excess sugar. And during this course, if the body finds that the fingers or other extremities provide a source of fluids/water, then it ciphens water from those areas and that leads to the drying out of that area. The diabetes can weaken other vital defenses too like the immune system that compound the problem (or led credibility to this theory). Regards, Rick – Hide quoted text — Show quoted text – > Can anyone tell me if certain meds can trigger P ? What are some of these > meds, and is naprosyn one of them ? > dennis g
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Thanks to all who have responded to my post regarding naprosyn and it’s possible triggering of P. dennis g
– Hide quoted text — Show quoted text -> I’m pretty sure I read somewhere it is a general trigger. > Use tylenol instead. > ok thank you
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- Hide quoted text — Show quoted text – > Thanks to all who have responded to my post regarding naprosyn and it’s > possible triggering of P. > dennis g > > I’m pretty sure I read somewhere it is a general trigger. > > Use tylenol instead. > were younger is it possible that strep throat occurs when you pick up a > cold or infection i find the moment istart medication rualide.Mayebe > naprosyn or any antibiotics out comes the psoraisis and as i am a non > insulan diabetic and suffer now and again from asthma maye ber its true > what our friend is saying about diabetes no one knows if they have > diabetes untill they check it out with a simple test.. thats how i found > it.is it true that lots of ps sufferers have diabetes???.. how many > psoraisis patients have had kidney stones ??Sea salt water is supposed to > be good ??Whats happening to the new amevive drug has anyone tried it > yet .with all the repetative mail coming in who has actualy been 100 > per cent cured.this group needs >positive feed back and cures .Dav is crap .all the steroids thgin the > skin andlight treat ment cyclos in meth tex ate and tigee son etc etc > all harm you and cost you megabucks over your life time all meds and > speciaists who prescribe the same ointments more than threetimes should be > sued by this group as they are charging you for the same old treatment > over your life time . act now and mail back if you think they are ripping > you off they should be struck off iff they are kind regards to all > DAVIDDDIOOOOOOOOOO
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> Can anyone tell me if certain meds can trigger P ? What are some of these > meds, and is naprosyn one of them ? > dennis g
Is Naprosyn the same as Naproxin? I take a 500 mg twice daily for generative arthritis and have noticed on increase in my numbers. I was taking it only when the joint pain got real bad, but my doctor advised me to take it twice a day, every day along with my Glucosomine/Chongroitan (or however you spell it). Some people have asked about that causing elevated numbers too. I guess that is one reason we so often say, "YMMV". Neither one has caused me any problems with my BG at all. Oh, in another answer I noticed someone recommended Tylenol to you. Before taking it on an ongoing basis I would advise checking with your doctor. It has been shown to cause liver damage in some patients, according to what my doctor says. He has told me to use it only very sparingly and very seldom. Best of luck to you. Chuck T2 9/96
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- Hide quoted text — Show quoted text -> Can anyone tell me if certain meds can trigger P ? What are some of these > meds, and is naprosyn one of them ? > dennis g > Is Naprosyn the same as Naproxin? I take a 500 mg twice daily for > generative > arthritis and have noticed on increase in my numbers. I was taking it only > when the joint pain got real bad, but my doctor advised me to take it twice > a > day, every day along with my Glucosomine/Chongroitan (or however you spell > it). Some people have asked about that causing elevated numbers too. I > guess > that is one reason we so often say, "YMMV". Neither one has caused me any > problems with my BG at all. > Oh, in another answer I noticed someone recommended Tylenol to you. Before > taking it on an ongoing basis I would advise checking with your doctor. It > has been shown to cause liver damage in some patients, according to what my > doctor says. He has told me to use it only very sparingly and very seldom. > Best of luck to you. > Chuck T2 9/96
Oops. Sorry. When I first wrote this I had just checked alt.support.diabetes since I have that too. As for whether or not Naproxin has aggravated my psoriasis, I would say I really don’t think so. I am sure I would have noticed it by now, and my dermatologist has a list of all medications I take, including supplements. He would have told me if any of them might aggravate it. He has told me that a couple of meds that I take may make my skin more light sensitive and I may burn more easily in my UVB cabinet. I hope this is of some help to you. Chuck Living with Psoriasis all of my 62 years.
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Yes they are the same. That’s the problem with p. and arthritis. What’s good for the arthritis is not necessarily good for the p. By the way, I was taking Tylenol like candy when I was pregnant for major headaches (under doctor’s orders – she told me not to worry about effects on me or the baby) and have never had any side effects. And the baby was and is still fine. – Hide quoted text — Show quoted text -> Can anyone tell me if certain meds can trigger P ? What are some of these > meds, and is naprosyn one of them ? > dennis g > Is Naprosyn the same as Naproxin? I take a 500 mg twice daily for generative > arthritis and have noticed on increase in my numbers. I was taking it only > when the joint pain got real bad, but my doctor advised me to take it twice a > day, every day along with my Glucosomine/Chongroitan (or however you spell > it). Some people have asked about that causing elevated numbers too. I guess > that is one reason we so often say, "YMMV". Neither one has caused me any > problems with my BG at all. > Oh, in another answer I noticed someone recommended Tylenol to you. Before > taking it on an ongoing basis I would advise checking with your doctor. It > has been shown to cause liver damage in some patients, according to what my > doctor says. He has told me to use it only very sparingly and very seldom. > Best of luck to you. > Chuck T2 9/96
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Can anyone tell me if certain meds can trigger P ? What are some of these meds, and is naprosyn one of them ? dennis g
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Ibuprofen is a trigger. – Hide quoted text — Show quoted text – > Can anyone tell me if certain meds can trigger P ? What are some of these > meds, and is naprosyn one of them ? > dennis g
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> Ibuprofen is a trigger.
Really? Can this tiggering be different in each person?
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I’m pretty sure I read somewhere it is a general trigger. Use tylenol instead. – Hide quoted text — Show quoted text -> Ibuprofen is a trigger. > Really? > Can this tiggering be different in each person?
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> I’m pretty sure I read somewhere it is a general trigger. > Use tylenol instead.
ok thank you
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